What Are Flavonoids? An Unbound, Untapped Potential

Here at Calm Collectiv, we love to chat all things cannabis. From CBD to terpenes, we have provided you with guides, thoughts and emerging ideas. Recently, the exciting topic of cannabis flavonoids came across our radar and we had to share with you, our devoted readers. So, what are flavonoids?

Flavonoids are the newest, hottest thing in the ever-expanding world of cannabis and their properties can help change the world. Why? Because according to emerging research, cannabis flavonoids, or cannaflavin, is sparking discussion around the novel, effective ways to treat pain. 

So What Is Cannaflavin Anyway?


A chemical found in every living plant on this planet, “flavonoids” are a key component of colour, a pigment in fruits and vegetables. On top of that, flavonoids, when harnessed correctly, can provide users with anti-oxidizing potential. 

Have you ever heard the phrases “eat by colour” or “superfoods”? Well, this is where the term originated! Most foods have their own varying properties, and thanks to flavonoids, there is a layer of a therapeutic value-added. There are nearly 6000 flavinoids identified across all fruit and vegetable species and in cannabis specifically, Cannaflavin A and it’s sister, Cannaflavin B are only two of twenty flavonoids found in all cannabis strains. Cannaflavins are known to work along with other flavonoids to give “distinctive aromas, tastes, and pigmentations to cannabis strains.” Founded in the 1980s by researcher Marilyn Barrett at the University of London, cannaflavonoids have proven to be around 30 times more powerful than your average dose of aspirin. 

The only problem? Cannaflavinoids only account for up to .014% of the fresh weight of the plant, and to experience the therapeutic, super anti-inflammatory effects of this, one must consume massive amounts of the flavonoid. According to this article, up until now, flavonoid production has just not been economically viable. To actually see and feel the effects of this supposed wonder drug, at this point, you’d ideally need to “consume something like 40 liters a day to reach therapeutic levels.” 

Interested in reading the entire study? Check it out here

Cannabis molecules don’t work alone. Together cannabinoids, terpenes, and flavonoids (pharmacologically active compounds found in cannabis), can bring some wonderful effects. Produced by the female cannabis plant trichomes, these compounds not only grow together but work together in magical ways, often known as the “entourage effect.” The synergy of all three provides a wide range of treatments and possibilities. Consuming them together in a “broad spectrum” form can mean triple the opportunity for healing, the calmness of mind and therapy. 

Flavonoids, A Turning Point?

what are flavonoids

New research coming out of the Canadian institution, Guelph University, there are new, more economically viable ways to harness the power of these important compounds. Using a combination of biochemistry and genomics and something called “in silico” computer genome mining, researchers were able to isolate the cannabis genes responsible for both Cannaflavin A and Cannaflavin B, the key flavonoids for pain management. These new findings are going to make it easier to artificially fabricate copious amounts of flavonoids, potentially making this an increasingly ubiquitous and accessible molecule – and opening the doors to more research. 

Next, following these discoveries, researchers filed patents that were quickly picked up by world-famous medical cannabis company Anahit International. Their goal: to dive deeper into the development of commercial flavonoid-based products. 

Why Is It Different Than Other Pain Management Options?

Why are companies like Anahit International seeing this as a massive opportunity? Molecules like cannabis flavonoids are reported to halt inflammation right at the source, without the toxicity that can be found with synthetic or lab-created pain-relieving medications. On top of it? It has little to no side effects since they are all-natural – including reduced risk of addiction. 

Thanks to former legislation, work on cannabis flavonoids had been stalled. It’s often shocking how much is being unlocked from one plant, and thanks to the changing times, we’re able to finally take a deeper look at the various permutations of cannabis. In effect, flavonoids can have the capacity to change the way that the world looks at pain management, and can ultimately help curb the burgeoning and devastating global opioid crisis. We’re excited to see what is next and are sure that there is more to come! Stay tuned! 

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